Kiwi Benefits: For Constipation, Two a Day Kept Pace With Mostly Low-Dose Fiber Supplements Over Weeks, Not 24 Hours. Against a Dummy, No Clear Difference Yet.

“The surprising benefits of kiwi for gut health and how it can improve your digestion in just 24 hours.” That line is from the description of “Eat THIS to Lose Fat, Prevent Disease, & Feel Better Now”, posted on 12 April 2025 by a physician-author’s food-and-health channel. It had 603,579 views when we read it on 10 October 2026 [1]. Two of the channel’s videos from May 2026 carry chapters called “The 24-Hour Kiwi Shift” and “The 24-Hour Gut Reset: Why You Should Eat a Kiwi Daily” [1].

It lands on a busy question. In the United States, “kiwi benefits” is searched about 49,500 times a month (from a paid keyword database, pulled 10 October 2026) [2].

So we read the research behind the fruit, which turned out to be mostly research about one thing. Here is the short version; the rest of the page is the working.

Two kiwifruit a day did about as well as a fiber supplement. In trials of adults with constipation, they added roughly one to three complete bowel movements a week to where people started, over four weeks, about what a fiber supplement did [3] [4].

Against a dummy, the fruit has not clearly won. The one randomised trial that compared it with a calorie-matched starch powder found no clear difference across everyone in it, in belly pain (by the team’s own 2026 congress abstract and a news report of its 2024 poster) or in bowel movements (by the news report); its small group with IBS-C did have less belly pain on the fruit [39] [40]. So the evidence is real, and not yet good enough to say the fruit itself relieves constipation.

The 24 hours is a different matter. We found no trial of the fruit that reported what happens on the first day; the trials counted in weeks [5].

Who paid matters here. Most of this research was paid for, at least in part, by a New Zealand kiwifruit marketer. The European food-safety regulator that read it still concluded the fruit works, and found no evidence that it does more than its fiber would [6].

What are the health benefits of kiwi fruit?

The one that has been tested most is the one above: going to the bathroom. Since 20 August 2025, sellers of fresh green kiwifruit in the European Union have been allowed to print “Consumption of green kiwifruit contributes to normal bowel function by increasing stool frequency”, as long as they add that the effect comes from 7 oz (200 g) of fresh kiwi flesh a day [7]. The date is our arithmetic: the regulation was published on 31 July 2025 and entered into force on the twentieth day after [7].

Mind the size. The trials used large fruit, 90 to 115 g of flesh apiece, so two came to about the 7 oz (200 g) the claim names [6]. A kiwifruit of the size the US Department of Agriculture uses as standard weighs 2.4 oz (69 g) [8]; it would take about three of those to make 200 g, by our arithmetic.

The rest of the “benefits” lists in the search results are mostly the nutrition label [2]. A green kiwifruit carries 92.7 mg of vitamin C and 3.0 g of fiber in every 3.5 oz (100 g); one of those standard 2.4 oz (69 g) fruits holds about 64 mg of vitamin C, by our arithmetic [8]. That is a fact about the fruit, not a health effect. The effects people ask about most, sleep, platelets and blood pressure, are further down, each rated on its own.

Does kiwi help with constipation?

Against a fiber supplement, about as well; against a dummy, not clearly. Here is how we know. The biggest trial ran in New Zealand, Italy and Japan from 2014 to 2017 [3]. It took 121 adults with constipation and 63 without. About half of the constipated group had functional constipation (constipation with no disease or drug behind it); the other half had IBS-C, irritable bowel syndrome with constipation, which is constipation that comes with belly pain [3]. It was a crossover trial: each person ate two green kiwifruit a day for four weeks and took 7.5 g of psyllium a day for four weeks, in an order decided by chance, with a four-week break between [3]. Psyllium is a fiber supplement made from seed husks and a standard first treatment for constipation; the two doses were matched to give about the same 6 g of fiber [3].

The count that mattered was complete spontaneous bowel movements: ones that came without a laxative and left the person feeling they had finished. Researchers count those because they are the ones that say constipation is easing. On kiwifruit, the constipated group gained 1.69 a week over where they started. On psyllium, they gained 0.90 [3]. The gap was small and only just on the “probably not chance” side of the line researchers use; split into the two kinds of constipation, neither gap cleared that line, and in the functional-constipation half psyllium’s own gain, 0.67 a week, did not clear it either [3]. Neither treatment was set against nothing, so these are gains over where people started, not proof of what caused them. The healthy volunteers went more often too, by about one a week on either [3].

Two things about that trial are worth knowing. The European regulator, which read it before it was published, noted that some psyllium effect may have carried over into the kiwifruit weeks and that two ways of analysing the numbers did not agree [6]. And the trial says in its own text that it was conducted “to establish further substantive evidence that could contribute to a positive opinion” from that regulator, and that its publication waited for the opinion [3].

Three more studies gave the fruit to people with constipation with no comparison group at all [9], and one compared it with dummy capsules without assigning people by chance, which is what makes a trial randomised; the regulator drew no conclusions from studies of either kind [6]. The trials that count are these.

The American trial gave 79 adults with chronic constipation two green kiwifruit a day, 12 g of psyllium or 3.5 oz (100 g) of prunes for four weeks [10]. It was not a clean comparison: the first 30 people were put on kiwifruit “to accommodate the limited growing season and fruit availability”, and only the rest were assigned by chance [9]. Kiwifruit came last of the three on the main measure: 13 of 29 people improved on it, against 14 of 22 on psyllium and 16 of 24 on prunes, a spread that could be chance [6]. Where it won was comfort: side effects were reported by 32% on kiwifruit, 45% on prunes and 66% on psyllium [9], and 68% of the kiwifruit group were satisfied with their treatment, against 48% on the other two, by the university’s account [11].

Two smaller New Zealand trials used gold kiwifruit. In one, two a day added about one complete bowel movement a week, and psyllium added about one and a half; the difference could be chance [12]. Its psyllium was matched to the gold fruit’s 2.5 g of fiber, which its authors say is below the recommended dose and list as a limitation [12]. In the other, 32 women with mild constipation went from 3.3 a week to 6.3 on three gold kiwifruit a day, and were at 4.5 at the end of their psyllium weeks, a rise on psyllium (5 g of fiber a day) that could have been chance [13].

Four trials of the whole fruit against a fiber supplement in adults with constipation (in one, the kiwifruit group was not chosen by chance)
Trial Kiwifruit, against what Complete bowel movements a week, change from where people started
New Zealand, Italy, Japan; 121 with constipation, plus 63 healthy; each person tried both for four weeks [3]Two green a day, against 7.5 g of psyllium+1.69 on kiwifruit, +0.90 on psyllium [3]
United States; 79 with chronic constipation, four weeks [10] [9]Two green a day, against 12 g of psyllium or 3.5 oz (100 g) of prunes; the first 30 people were put on kiwifruit, not assigned by chance [9]+1.0 on kiwifruit, +1.7 on psyllium, +2.7 on prunes; the share of people who improved did not differ clearly [6]
New Zealand; 24 with constipation, plus 32 healthy; each tried both [12]Two gold a day, against 7.5 g of psylliumAbout +1.0 on kiwifruit, about +1.6 on psyllium; no clear difference [12]
New Zealand; 32 women with mild constipation; each tried both [13]Three gold a day, against a branded psyllium powder (5 g of fiber)From 3.3 to 6.3 on kiwifruit; 4.5 at the end of the psyllium weeks [13]
All four compared the fruit with a fiber supplement; none compared it with doing nothing or with a dummy. All four had money, fruit or staff from the same New Zealand kiwifruit marketer. These are averages for groups, not a forecast for any one person.

Pool them and the picture turns out to be one trial. A 2024 review for the British Dietetic Association combined three of these trials and reported that kiwifruit added 0.36 bowel movements a week more than psyllium [9]. That is about one extra every three weeks, by our arithmetic. The range the true answer probably sits in, by the review’s figures, ran from 0.24 to 0.48 [9]. But the review’s own chart, which also holds a trial of prunes, gives 98.5% of its weight to one of these three, the biggest trial’s group with functional constipation; the other two pointed opposite ways, one a bowel movement a week ahead on kiwifruit and one half a bowel movement behind, both well within chance [9]. The pooled figure is that one group’s figure. Its narrow range rests on a spread of 0.31 bowel movements a week entered for both groups, less than a tenth of the spread in the other two trials, which looks like a standard error (how precisely an average is known) rather than how much people differed. If it is one, the range would run from about half a bowel movement fewer to a little over one more a week, which takes in no difference at all; that arithmetic is ours [9]. The trial’s own paper found no significant difference between kiwifruit and psyllium in how often people went in any week [3], and the European regulator noted that counting raw weekly stools, rather than gains, gave no clear difference [6]. The Association’s guideline graded that evidence “low”, its word for a result that further trials could well change, and still says two to three kiwifruit a day for at least four weeks “may be recommended”, and that kiwifruit may suit people better than psyllium if psyllium gives them bloating, pain or gas [4].

Two more reviews agree on the direction and on the weakness. A 2022 pooling of seven randomised trials found low-certainty evidence that kiwifruit helps, and every trial in it that used a dummy comparison tested capsules or powders, not the fruit [14]. A 2026 network meta-analysis, a method for ranking several options against each other across many trials at once, ranked “fruit-based foods” above fiber supplements and above a dummy for how often people went [15]. Its own supplementary tables show what that rests on: its kiwifruit trials were all compared with psyllium, and its one trial of a fruit against a dummy was a fig paste [15]. Not every pooling agrees. A 2024 meeting abstract that pooled eight trials of the fruit and its extracts together concluded that in people with constipation there was “no evidence” they add complete bowel movements against a dummy or psyllium [41]. It does not name its trials, and one of its own ranges, 0.01 to 0.36, sits beside the words “did not significantly affect”, so we could not check it [41].

Which leaves one more reader to hear from. The European regulator was asked by the marketer in 2020 to approve a claim about kiwifruit and the gut. It set aside most of the 18 studies it was sent, found faults in all six it used, and still concluded that “a cause and effect relationship has been established” between green kiwifruit and normal bowel movements [6]. In the four studies of healthy people, it worked out roughly half an extra stool to two extra stools a week; in people with constipation, kiwifruit did at least as well as the comparison treatment [6]. And then this sentence: “the scientific evidence does not establish that the effect of green kiwifruit on normal defecation is over and above what could be expected by its content in dietary fibre” [6].

One trial has asked the plainer question: does the fruit beat nothing? In Christchurch, New Zealand, 63 adults with constipation were assigned by chance to two green kiwifruit a day or a calorie-matched starch powder (maltodextrin) for four weeks; everyone knew which they were getting, and the main measure was belly pain [40] [39]. The team showed its first results on a poster at a gastroenterology meeting in May 2024, three years after the regulator’s opinion. The poster’s abstract is printed in the meeting’s journal supplement, but the publisher’s pages served us bot checks and no index or archive we tried held its text, so we have not read it [42]. A medical news service’s report of the poster says that across the 57 people analysed there was no significant difference in belly pain, in total bowel movements (p = 0.46) or in complete bowel movements (p = 0.07, just short of the line for “probably not chance”), while the 18 with IBS-C did better on belly pain and constipation scores [40]. The report quotes the team describing “a clinically relevant impact on complete spontaneous bowel movements”; the p-value it gives for that measure is the 0.07 above [40]. The team’s own abstract for a European nutrition congress in September 2026 gives the main measure the same shape: across 52 people, belly-pain scores fell by 0.48 on the fruit and 0.33 on the powder, a gap that could easily be chance (p = 0.48); in 17 with IBS-C, by 0.86 against 0.17 (p = 0.024) [39]. Neither report says how many more bowel movements the fruit produced, if any. Both report scans showing more water in the colon on the fruit [40] [39]. A gap inside a small subgroup is a lead, not a finding: cut a trial into enough slices and one of them will clear the line by chance.

Does kiwi work in 24 hours?

Not that any trial of the fruit has shown, because none we found looked that closely. The constipation trials of whole kiwifruit we read kept daily diaries and reported them as averages over a week or longer [3] [10] [12] [13] [5]. The quickest look was the first-week average in the biggest trial, which had already risen, on kiwifruit and on psyllium alike, by the trial’s own chart [3]. A week is not a day.

The fastest measurements of the fruit came from a Nottingham MRI study [16]. Fourteen healthy volunteers, median age 26, ate two large green kiwifruit twice a day, four a day, for two days, then were scanned every hour on the third day [16]. Water in the small intestine was higher than on a calorie-matched control drink at every scan after the fasting one, and the authors think the effect “disappears overnight” [16]. The trial’s main measure, how watery the contents of the first stretch of the colon were across the whole day, came out at p = 0.056, just the wrong side of the line researchers use for “probably not chance”; the abstract leads with the second half of the day, where it cleared the line [16]. Stools ran at 1.46 a day against 1.14, counted over days three to six, not the first day [16].

If “digestion” means digesting a meal, there are two quicker studies, both small and both comparing one kind of kiwifruit with another. Ten healthy men ate a 14 oz (400 g) steak with two green or two gold kiwifruit: bloating was lower with the green, and the stomach emptied no faster [17]. Twelve older adults ate beef after 14 days of each kind: amino acids, the building blocks of protein, reached the blood faster with the green, and the total absorbed was the same [18]. Green kiwifruit carries an enzyme that breaks down protein, actinidin; the gold variety in those studies had none [18].

So where does a day come from? The one trial we found that reported the first 24 hours tested capsules of a kiwifruit extract, not the fruit, in 58 people in China with constipation that had started recently [19]. Its authors, led by the extract maker’s chief scientific officer, wrote that people improved “within the first 24 hours of consumption of the kiwifruit extract” [19]. They also wrote this: “Within 24 hours of starting the placebo, participants were experiencing an increase in bowel movement, improvement in abdominal discomfort and a softening of the stool” [19]. The people on dummy capsules improved on day one too; the authors suggest some were getting better on their own, and the improvement on the dummy faded over several days [19]. The same maker’s patent, granted in 2016, describes nursing staff counting bowel movements in the 24 hours after doses of its extract drinks, in elderly people aged 65 to 95 at three facilities [20]. Neither is the fruit, and the patent is not a trial.

We could not trace where the channel’s 24 hours came from. None of the three video descriptions cites a study [1].

Kiwi pills, powders and extracts are a different claim

The European authorisation covers fresh green kiwifruit only. The regulation says the regulator could draw no conclusions from the studies of other kiwifruit foods [7]. The British guideline is blunter: kiwifruit supplements “do not impact stool frequency or stool consistency in constipation” [4]. Pooled, they changed how often people went by 0.24 a week, with a range from 0.32 fewer to 0.80 more: “does nothing” sits inside it [4].

The extract trials we read, one by one, are a study in who runs them. A capsule trial paid for by one extract company found no difference from a dummy in any week [21]. Another company paid for and supplied a six-week trial of a green-kiwifruit extract in 64 healthy adults with mild gut discomfort, 41 of whom finished: how often people went changed in neither group, though some symptom scores improved from where people started only on the extract [43]. A powder trial sponsored by the maker of the extract in the 24-hour trial above found more bowel movements than on a dummy in weeks two to four, on one measure or another; after its first 50 people it ran an interim check and, it says, “It was determined that additional subjects would be necessary to reach statistical significance”, and it went on to 87 [22]. The same maker paid for a trial of 186 adults with IBS-C, enrolled from 2013 to 2015 and published in 2025: it missed its primary endpoint, the main result it was designed to judge itself by, 24% against 26% on the dummy, while more people on the extract went more often, 54% against 36% [23]. A 2024 Indian trial tested a kiwi-pulp drink made and sold by a company whose research staff are two of its authors; it was run at a clinic whose founder is the lead author, and it declares no conflicts of interest [24]. And the largest extract trial of all, of two kiwifruit powders, was registered by an industry sponsor as 240 people at one Canadian centre, started in March 2018, and lists no results [25]. It has been published, in a journal PubMed does not index, which is why our first searches missed it [5]. A 2023 paper’s chart of who took part shows 288 people assigned by chance to seven groups: a green or a gold powder at two doses each, a formula, or one of two dummy powders [44]. The papers and the registration do not match: 288 people against 240, seven groups against six, and four centres in the 2025 paper against one [25] [44]. A 2024 paper’s title says 600 mg a day of the green powder “improves stool form and relieves occasional constipation” [45]. A 2025 paper, whose abstract names the registration, compared 600 mg a day of the gold powder with a dummy in 85 people and was designed around complete bowel movements; its abstract says they improved “over baseline”, that is, against where people started, and gives no comparison with the dummy on that measure [46]. The publisher refused our automated reading and we found no other copy, so we have read only their titles, that one abstract and their charts, and cannot say what they found against the dummies. Their authors include staff of the trial’s registered sponsor, of the research firm that ran it, and of the New Zealand company that supplied the same powders to an earlier trial [44] [45] [46] [47].

For more on what sells as a gut supplement, the site’s ranking of gut-health supplements puts each against its trials.

Who paid for the kiwi research?

Here is the count. Of the nine studies on this page that gave people whole kiwifruit to test the gut, all nine had money, fruit or staff from the New Zealand marketer, which one of the papers describes as “a consortium of kiwifruit growers” [16]. It was the principal sponsor of the biggest trial, with two of its employees among the authors [3]; it paid for the MRI and steak studies, each with an employee as an author [16] [17], and the protein study [18]; it co-funded the two gold trials with the New Zealand government [12] [13]; it part-funded the American trial, by the university’s own account [11]; and it supported the first trial, in 2002 [26], and co-funded the trial against a starch powder described above, supplying its fruit [27].

Industry money does not make a result wrong. It is why the funding is on this page, and why the independent readings matter: a regulator, a dietetic guideline and three reviews read these trials and concluded that the fruit helps, the guideline and the 2022 review grading the evidence low [6] [4] [9] [14] [15]; the 2024 meeting abstract above concluded the opposite, in a form we could not check [41]. Four of the whole-fruit trials compared kiwifruit with psyllium, a choice one team explained by saying a fruit “cannot be easily adequately matched by a simple control material for a placebo” [12]. That is fair, and it means what those trials show is that the fruit does about as well as psyllium at the doses they used, and three of the four gave psyllium at 6 g of fiber a day or less, below the more than 10 g a day at which the dietetic guideline’s pooling found fiber supplements beat a dummy; one team calls its own dose below the recommended dose, while the largest trial’s authors held that 6 g was enough [3] [4] [12] [13]. The one randomised trial we found that pits the fruit against a dummy has reported only in a poster, a congress abstract and a news report, and across everyone in it found no clear difference [40] [39].

Is it the kiwi, or just the fiber?

This section is the desk’s own reasoning, and it is labelled as such. The regulator’s sentence about fiber [6] is the question the evidence leaves open. Three answers, each rated.

Answer one: it is mostly the fiber. Two of the large green kiwifruit in the biggest trial carry about 6 g of it, and that trial matched it with psyllium; the gold trials matched smaller amounts, 2.5 g and 5 g; and the results came out close [3] [12] [13]. The regulator could find nothing beyond it [6]. This is the regulator’s reading of the trials, which is as close to a measurement as this question has come.

Answer two: the fruit’s fiber holds more water than a spoonful of powder. The MRI study’s authors cite laboratory work in which kiwifruit cell walls swelled to more than three times their volume, about one and a half times as much as psyllium, and their scans showed the small intestine holding more water all day [16]. That could explain an edge over psyllium, if there is one. The swelling and the water are measured: in a lab, in 14 healthy people, and, as more water in the colon, in the trial against a starch powder [39]; that they explain the edge in people with constipation is a surmise.

Answer three: it is the enzyme. This is the version that sells “digestion”, and the evidence mostly leans against it. Gold kiwifruit has about an eighth of the green’s enzyme activity, by the gold trial’s own account [12], and people with constipation went more often on gold kiwifruit in both of its trials [12] [13]. The same paper mentions, as an unpublished result, that an older gold variety with no enzyme activity did not relieve gut discomfort, which points the other way; an unpublished result is one we cannot check [12]. The enzyme’s measured effects are on how a protein-heavy meal is handled, not on constipation [18] [17]. And actinidin is the fruit’s main allergen, linked to its most severe reactions [28]. This is a surmise from two small trials that never set out to test the enzyme, with one unchecked result on the other side.

Put the three together and here is what we think is true, stated plainly so you can disagree with it: two kiwifruit a day are a fiber supplement you can peel. They did about as well as one, mostly at low doses, in the trials, over about the same weeks, though against a dummy the fruit has not yet clearly won; the 24 hours, the enzyme and the “gut reset” are packaging until someone tests them.

What we could not find, and would like to. The full paper of the one randomised trial of the whole fruit against a dummy. Its last data were collected on 13 July 2022 [29]; its protocol, published in 2026, says the analysis is complete and the results were expected by April 2026 [27]; so far we have found only the poster, the congress abstract and the news report above [5]. It should say how many more bowel movements, if any, the fruit produced than the starch powder, which neither report gives. We would also like a trial of the whole fruit that counts the first day, and to read the three papers from the powder trial in full [44] [45] [46]. If you know of any of them, the corrections line on this site is open.

Can kiwi help you sleep?

Maybe a little; the evidence is small and points both ways. The earliest study we found is a 2011 Taiwanese one: 24 adults with sleep problems, 22 of them women, ate two kiwifruit an hour before bed for four weeks and reported sleeping better; their sleep-questionnaire score improved by 42.4%, and their total sleep time rose by 13.4% by their own diaries and by 16.9% by a wrist monitor [30]. There was no comparison group, the authors say they could not tell how much was expectation, and the study was supported by the kiwifruit marketer’s office in Taiwan [30].

The trials since then disagree. In a Norwegian randomised trial of 74 students with insomnia symptoms, 4.6 oz (130 g) of kiwi an hour before bed for four weeks did better than the same amount of pear on 2 of 12 measures, both from sleep diaries, and on none measured by wrist monitor [48]. In a randomised trial of 26 Saudi female students, sleep improved over six weeks in the kiwifruit group and in the comparison group alike, with no difference between them [31]. In 24 young New Zealand men, one evening of two fresh kiwifruit did not change how long they slept by wrist monitor, against water; some morning ratings were better after a dried-kiwi drink [32]. In 36 children aged 8 to 12 with overweight and sleep problems, kiwifruit plus a soccer programme improved sleep more than soccer alone [33]. Rated alone: Preliminary. The site’s melatonin verdict weighs the best-known sleep supplement.

Kiwi benefits for platelets

Two different questions travel under this search. The first is whether kiwifruit makes platelets, the blood cells that start a clot, less likely to clump. Two trials from one Oslo group say a little: healthy volunteers eating two or three kiwifruit a day for 28 days had an 18% smaller clumping response than in their comparison period [34], and in a trial of 102 male smokers, the group given three a day for eight weeks had 15% less [35]. We read both as abstracts. Rated alone: Preliminary.

The second question, which circulates around dengue fever, is whether kiwifruit raises a low platelet count. The one trial we found gave 100 patients in a hospital in Pune, India, with low counts from dengue or another viral fever, either green kiwi or guava, 3.5 to 10.6 oz (100 to 300 g) a day depending on appetite, with no group that ate neither [49] [5]. Counts in the kiwi group dropped over the first few days before they rose, and the guava group recovered sooner [49]. It cannot answer the question. With no group that ate neither fruit, it cannot say whether either raised anything; the two groups did not start alike (12 of the 50 on guava began in the paper’s lowest band of counts, under 20,000, against 1 of the 50 on kiwi); everyone knew which fruit they were eating; and it was registered for 40 patients and reports 100 [49]. Rated alone: Unsupported, of the tested kind: tested once, against another fruit, and nothing in that test supports it. What to eat during dengue fever is a question for the clinician treating it.

Does kiwi lower blood pressure?

The site’s blood-pressure verdict already weighs it, with the pooled kiwifruit trials and the largest of them, and rates the fruit’s effect Preliminary. We have not repeated that work here.

Which is healthier, apple or kiwi?

Neither has been tested against the other for constipation in any trial on this page. On the label, per 3.5 oz (100 g), green kiwifruit has 92.7 mg of vitamin C to an apple’s 4.6 mg, 3.0 g of fiber to 2.4 g, and 312 mg of potassium to 107 mg [8] [36]. “Healthier” is not something those numbers settle, but for vitamin C it is not close.

Who these studies were done on

Mostly women, mostly under 65, mostly with mild constipation. Women were 74% of the biggest trial and 82% of its constipated group; its volunteers were 18 to 65, and anyone with severe IBS symptoms was turned away [3]. Most of the trials, a 2022 review notes, took people with occasional or mild constipation [14]. The American trial was 87% women [10]; one gold trial was all women [13]; the other’s constipated volunteers were over 90% women [12]. The one bowel-habit trial of older people we read gave 38 healthy adults over 60 a kiwifruit for every 66 lb (30 kg) of body weight, and they went more often [26].

Some people were left out on purpose. The two largest trials excluded women who were pregnant or breastfeeding [3] [37], so the searches for “kiwi benefits pregnancy” land on a population these trials did not test. The American trial also excluded anyone taking opioid painkillers and anyone with warning signs such as bleeding or unexplained weight loss [37]; those are questions for a clinician, not a fruit bowl. A 2022 review that put no limit on age included no trial in children [14]; a children’s trial of a kiwifruit-extract chew against a standard laxative is registered and was listed as not yet recruiting [38]. None of the trials we read reported men and women separately, and there were few men in them.

People with a kiwi allergy are the clearest exception. Kiwifruit has become one of the main plant foods people are allergic to [28]. Its main allergen is actinidin, the same enzyme in the digestion story; it makes up about half of the fruit’s soluble protein and is linked to the most severe reactions [28]. Reactions run from an itchy mouth to anaphylaxis, children are more likely than adults to react in several parts of the body at once, and people allergic to latex, birch or grass pollen, banana or avocado can react to kiwifruit too [28]. The biggest constipation trial excluded anyone with a known kiwifruit or latex allergy [3].

Where “kiwi fixes your digestion in 24 hours” came from

The research came first, and it came from New Zealand. In 2002 a trial titled “Kiwifruit promotes laxation in the elderly” gave 38 healthy people over 60 kiwifruit for three weeks; they went more often, and the study was supported by a university, a cancer charity and the kiwifruit marketer [26]. In the younger group the same paper describes, how often people went did not change [26]. Nineteen years later the regulator called the statistics in both studies “not interpretable” [6].

Then the framing, which went through a regulator. The marketer’s 2020 application first asked to say that “Regular consumption of green kiwifruit contributes to gastrointestinal comfort” [6]. The regulator narrowed it to bowel movements in 2021, the big trial was published once that opinion was in [3], and in 2025 the European Commission authorised the stool-frequency wording, for the fresh fruit, at 7 oz (200 g) a day [7]. The American trial reached the public through a university news item in November 2020 [11].

The earliest 24-hour counts we found belong to the extract business: an extract maker’s 2016 patent counting bowel movements in the 24 hours after a dose [20], and the same maker’s 2018 trial, in which people on dummy capsules also improved within a day [19]. Whether either reached the channel we cannot say. The channel’s video from April 2025 put the 24 hours on the fruit itself, and two videos in May 2026 made it a chapter title [1]. In the search results for “kiwi benefits”, as they appear there, a hospital’s “10 Benefits of Kiwi Fruit for Health” lists “aids digestion”, and a national newspaper’s “Why a Kiwi May Be the Perfect Snack” carries the line that kiwi fiber helps “address constipation” [2].

None of this is aimed at anyone with a bowl of kiwifruit on the counter. Two or three a day for ordinary constipation is what a dietetic guideline suggests, on the evidence above [4]. It is the 24-hour stopwatch that the evidence does not carry.

What this is rated, and what the rating covers

Preliminary — for the claim that eating kiwifruit relieves constipation.

It is rated Preliminary because the trials are real and point the fruit’s way, but they are not yet good enough to show it does more than nothing. Three randomised trials, and one in which the kiwifruit group was not chosen by chance, found more complete bowel movements on two or three kiwifruit a day than at the start, about as many as on a fiber supplement [3] [10] [12] [13]. None of the four had a group given nothing, so they show gains over where people started rather than what caused them, and three of them gave psyllium at 6 g of fiber a day or less, below the more than 10 g a day at which the dietetic guideline found fiber supplements beat a dummy [3] [4] [12] [13]. The pooled edge over psyllium is one trial’s figure, with a precision that looks too good [9]. The one randomised trial against a dummy, a calorie-matched starch powder, found no clear difference across everyone in it, in belly pain, its main measure, by its team’s congress abstract and a news report of its poster, or in bowel movements, by the news report; we have not found its full paper [39] [40] [27] [5]. On the other side, a European regulator in 2021 and a dietetic guideline in 2025 concluded that the fruit helps, the guideline grading the evidence low; neither cites the trial against a starch powder [6] [4]. The trials were small, could not hide from people what they were eating, took mostly women with mild constipation, and every one of them had money from the kiwifruit marketer [3] [11] [12] [13]. The rating would move to Supported if the dummy-controlled trial’s full results, or a second trial like it, showed the fruit clearly ahead on bowel movements.

Rated alone, in words. That two kiwifruit a day do about as well as psyllium at the doses those trials used, over four weeks: Preliminary. In four small trials the fruit was never clearly behind psyllium and was ahead on complete bowel movements in two, but three of the four gave psyllium at 6 g of fiber a day or less, a dose at which the dietetic guideline’s own pooling found fiber supplements no better than a dummy, and none was built to show the two are equal [3] [4] [10] [12] [13]. That kiwifruit works “in just 24 hours”: Unsupported, of the untested kind; no trial of the fruit we found reported the first day, and the one extract trial that did saw its dummy capsules work that fast too [5] [19]. An untested claim is not a disproven one. That kiwifruit capsules, powders or extracts relieve constipation: Preliminary; the trials conflict, the most positive were paid for by a maker, the largest reports its main measure, in the one abstract we could read, only against where people started, and the independent pooling found no change in how often people went [4] [21] [23] [43] [46]. That kiwifruit makes a meal’s protein digest faster: Preliminary, two small studies comparing one kiwifruit with another [17] [18]. Sleep: Preliminary. Platelets clumping less: Preliminary. Raising a low platelet count: Unsupported, of the tested kind; the one trial we found set kiwi against guava, with no group given neither [49]. Blood pressure: Preliminary, on the site’s own verdict.

What is not rated here: kiwi for immunity, skin, weight loss or cancer, which this page did not weigh; the comparison with prunes, which did better than kiwifruit on the numbers in the American trial, though not by a clear margin, and is its own question; and the frame above, which is this desk’s reasoning from the evidence rather than a result the evidence delivered. It is marked as ours so that you can weigh it as ours. This is journalism, not medical advice: constipation that is new, severe or comes with warning signs is a reason to see a clinician. The site’s psyllium verdict rates what that supplement does for cholesterol, and the fiber verdict what fiber does for weight. How we read a study, and what each tier means, is set out here.

Sources
[1] A physician-author’s food-and-health channel: three videos, published 12 April 2025, 23 May 2026 and 20 May 2026, with 603,579, 148,937 and 85,901 views. Titles, dates, view counts, chapter titles and descriptions read through the YouTube Data API at 01:43:45 UTC on 10 October 2026; we read the descriptions, not the videos’ audio. The channel is described by its role, not its name.
[2] Search data from a paid keyword database, pulled 10 October 2026: monthly search volumes for the United States, and Google’s results, People Also Ask questions and related searches for “kiwi benefits” (03:50:51 UTC). Kept with this page’s records.
[3] Gearry R, Fukudo S, Barbara G, Kuhn-Sherlock B, Ansell J, Blatchford P, et al. Consumption of 2 green kiwifruits daily improves constipation and abdominal comfort—results of an international multicenter randomized controlled trial. American Journal of Gastroenterology 2023;118(6):1058–1068. 184 adults in New Zealand, Italy and Japan. Read in full on PubMed Central, its tables as images. doi:10.14309/ajg.0000000000002124
[4] Dimidi E, van der Schoot A, Barrett K, Farmer AD, Lomer MC, Scott SM, Whelan K. British Dietetic Association guidelines for the dietary management of chronic constipation in adults. Journal of Human Nutrition and Dietetics 2025;38(5):e70133. Four systematic reviews, 75 trials. Read in full on PubMed Central. doi:10.1111/jhn.70133
[5] The desk’s searches, 10 October 2026: PubMed by title and abstract in several wordings (kiwifruit, kiwi fruit, kiwis, Actinidia, Chinese gooseberry, with bowel, stool, constipation, laxation, defecation, sleep, platelet, dengue and thrombocytopenia terms; 110 records for the main bowel search, every title read); Europe PMC; ClinicalTrials.gov (“kiwifruit”, “kiwi fruit”, “kiwifruit constipation”, “kiwi platelet”, “kiwifruit dengue”); the Australian New Zealand trial registry; the tables of included studies in the 2024 and 2026 reviews, the 2022 review and the European regulator’s list of 18 studies; and one ordinary web search per claim, its first page read. After an independent review found trials in journals PubMed does not index, the searches were run again in OpenAlex, an index that holds many such journals (kiwifruit, kiwi and the genus name with constipation and bowel terms, maltodextrin, platelets and dengue, sleep, and the powders’ brand names), with fresh web searches, and the Indian trial’s registry record was read through the World Health Organization’s trial-search portal. The record is kept with this page.
[6] EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA). Green kiwifruit (lat. Actinidia deliciosa var. Hayward) and maintenance of normal defecation: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006. EFSA Journal 2021;19(6):6641. Adopted 7 May 2021, on an application received 19 August 2020. Read in full on PubMed Central. doi:10.2903/j.efsa.2021.6641
[7] Commission Implementing Regulation (EU) 2025/1560 of 30 July 2025 authorising a health claim made on foods, other than those referring to the reduction of disease risk and to children’s development and health, and amending Regulation (EU) No 432/2012. Official Journal of the European Union L, 31 July 2025. Read in full in the Internet Archive’s copy of EUR-Lex, saved 11 November 2025.
[8] US Department of Agriculture, FoodData Central: Kiwifruit, green, raw (SR Legacy, FDC ID 168153). Per 100 g: vitamin C 92.7 mg, dietary fiber 3.0 g, potassium 312 mg, 61 kcal; one fruit of 2-inch diameter, 69 g. Read 10 October 2026.
[9] van der Schoot A, Katsirma Z, Whelan K, Dimidi E. Systematic review and meta-analysis: foods, drinks and diets and their effect on chronic constipation in adults. Alimentary Pharmacology & Therapeutics 2024;59(2):157–174. 23 studies, seven of them of kiwifruit. Read in full in the Internet Archive’s copy of the publisher’s page, saved 6 November 2023. doi:10.1111/apt.17782
[10] Chey SW, Chey WD, Jackson K, Eswaran S. Exploratory comparative effectiveness trial of green kiwifruit, psyllium, or prunes in US patients with chronic constipation. American Journal of Gastroenterology 2021;116(6):1304–1312. 79 adults. Read in its published abstract; the full text is behind the publisher’s paywall, and its design and results are also taken from the readings in [6] and [9]. doi:10.14309/ajg.0000000000001149
[11] Michigan Medicine, Health Lab. Does kiwifruit help chronic constipation? 20 November 2020. The university’s news item on the trial in [10]. Read in the Internet Archive’s copy, saved 24 July 2026.
[12] Bayer SB, Heenan P, Frampton C, Wall CL, Drummond LN, Roy NC, Gearry RB. Two gold kiwifruit daily for effective treatment of constipation in adults—a randomized clinical trial. Nutrients 2022;14(19):4146. 56 adults, 24 of them constipated. Read in full on PubMed Central. doi:10.3390/nu14194146
[13] Eady SL, Wallace AJ, Butts CA, Hedderley D, Drummond L, Ansell J, Gearry RB. The effect of ‘Zesy002’ kiwifruit (Actinidia chinensis var. chinensis) on gut health function: a randomised cross-over clinical trial. Journal of Nutritional Science 2019;8:e18. 32 women. Read in full on PubMed Central. doi:10.1017/jns.2019.14
[14] Eltorki M, Leong R, Ratcliffe EM. Kiwifruit and kiwifruit extracts for treatment of constipation: a systematic review and meta-analysis. Canadian Journal of Gastroenterology and Hepatology 2022;2022:7596920. Seven trials, 399 people. Read in full on PubMed Central. doi:10.1155/2022/7596920
[15] Mou J, Zeng L, Li Y, He S, Hu K, Wang Q. Efficacy of dietary interventions for functional constipation: a systematic review and network meta-analysis. American Journal of Clinical Nutrition 2026;123(5):101277. 19 trials, searched to 20 August 2025. Read as its abstract, its published figures and its supplementary tables, which list the included trials; the article text is behind the publisher’s paywall. doi:10.1016/j.ajcnut.2026.101277
[16] Wilkinson-Smith V, Dellschaft N, Ansell J, Hoad C, Marciani L, Gowland P, Spiller R. Mechanisms underlying effects of kiwifruit on intestinal function shown by MRI in healthy volunteers. Alimentary Pharmacology & Therapeutics 2019;49(6):759–768. 14 healthy adults. Read in full on PubMed Central. doi:10.1111/apt.15127
[17] Wallace A, Eady S, Drummond L, Hedderley D, Ansell J, Gearry R. A pilot randomized cross-over trial to examine the effect of kiwifruit on satiety and measures of gastric comfort in healthy adult males. Nutrients 2017;9(7):639. 10 men. Read in full on PubMed Central. doi:10.3390/nu9070639
[18] Park S, Church DD, Starck C, Schutzler SE, Azhar G, Kim IY, et al. The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism. European Journal of Nutrition 2021;60(2):1141–1148. 12 older adults. Read in full on PubMed Central. doi:10.1007/s00394-020-02363-5
[19] Weir I, Shu Q, Wei N, Wei C, Zhu Y. Efficacy of actinidin-containing kiwifruit extract Zyactinase on constipation: a randomised double-blinded placebo-controlled clinical trial. Asia Pacific Journal of Clinical Nutrition 2018;27(3):564–571. 58 adults. Read in full in the journal’s own copy. doi:10.6133/apjcn.122017.03
[20] United States Patent 9,320,781 B2. Dietary supplement for managing gut health. Filed by the maker of a kiwifruit extract; granted 26 April 2016. Read in the text of Google Patents’ copy, 10 October 2026. A patent’s examples are not peer-reviewed trials.
[21] Kindleysides S, Kuhn-Sherlock B, Yip W, Poppitt SD. Encapsulated green kiwifruit extract: a randomised controlled trial investigating alleviation of constipation in otherwise healthy adults. Asia Pacific Journal of Clinical Nutrition 2015;24(3):421–429. 40 adults. Read in full in the journal’s own copy. doi:10.6133/apjcn.2015.24.3.15
[22] Udani JK, Bloom DW. Effects of Kivia powder on gut health in patients with occasional constipation: a randomized, double-blind, placebo-controlled study. Nutrition Journal 2013;12:78. 87 adults. Read in full on PubMed Central. doi:10.1186/1475-2891-12-78
[23] Holtmann G, Talley NJ, Nandurkar S, Gibson PR. Randomized, placebo-controlled, double-blind 8-week trial on the efficacy of a proprietary kiwifruit extract on constipation-predominant irritable bowel syndrome. JGH Open 2025;9(8):e70250. 186 adults, enrolled December 2013 to July 2015. Read in full on PubMed Central. doi:10.1002/jgh3.70250
[24] Porwal AD, Gandhi PM, Kulkarni DK, Bhagwat GB, Kamble PP. Effect of KiwiBiotic on functional constipation and related symptoms: a prospective, single-center, randomized, comparative, crossover study. World Journal of Gastrointestinal Pharmacology and Therapeutics 2024;15(5):97330. 70 adults. Read in full on PubMed Central. doi:10.4292/wjgpt.v15.i5.97330
[25] ClinicalTrials.gov NCT03462199. A single-center, randomized, double-blind, placebo-controlled, parallel study to evaluate the efficacy of the investigational products on complete spontaneous bowel movements. Industry sponsor; registered as a single-centre trial in Canada, started in March 2018; 240 enrolled; completed 3 February 2020; no results posted, and no publication linked. The 2025 paper in [46] names this registration; the 2023 and 2024 papers in [44] and [45], by the same authors, report the same powders, doses and design. Record read 10 October 2026.
[26] Rush EC, Patel M, Plank LD, Ferguson LR. Kiwifruit promotes laxation in the elderly. Asia Pacific Journal of Clinical Nutrition 2002;11(2):164–168. 38 healthy adults over 60. Read in full in the journal’s own copy. doi:10.1046/j.1440-6047.2002.00287.x
[27] Maggo J, Ng HM, Bayer SB, Wall CL, Hoad CL, Marciani L, et al. Normalization of gastrointestinal symptoms in adults with constipation with daily green kiwifruit consumption: protocol for an open-label intervention study. JMIR Research Protocols 2026;15:e75286. Read in full on PubMed Central. doi:10.2196/75286
[28] Bringheli I, Brindisi G, Morelli R, Marchetti L, Cela L, Gravina A, et al. Kiwifruit’s allergy in children: what do we know? Nutrients 2023;15(13):3030. A review. Read in full on PubMed Central. doi:10.3390/nu15133030
[29] Australian New Zealand Clinical Trials Registry ACTRN12621000621819. Kiwifruit Ingestion to Normalise Gut Symptoms in the Christchurch IBS cohort. Completed; last data collected 13 July 2022; no results documents uploaded; record last updated 14 February 2025. Read 10 October 2026.
[30] Lin HH, Tsai PS, Fang SC, Liu JF. Effect of kiwifruit consumption on sleep quality in adults with sleep problems. Asia Pacific Journal of Clinical Nutrition 2011;20(2):169–174. 24 adults. Read in full in the journal’s own copy. PMID 21669584
[31] Noorwali EA, Noorwali NM, Aljaadi AM, Shuaib S, Alrehili S, et al. The effect of kiwifruit consumption on sleep quality, fatigue, and BMI in Saudi students with poor sleep quality: a 6-week pilot randomized controlled trial. Nutrire 2024;49(2). 26 women. Read in its published abstract. doi:10.1186/s41110-024-00297-0
[32] Kanon AP, Giezenaar C, Roy NC, McNabb WC, Henare SJ. Acute effects of fresh versus dried Hayward green kiwifruit on sleep quality, mood, and sleep-related urinary metabolites in healthy young men with good and poor sleep quality. Frontiers in Nutrition 2023;10:1079609. 24 men. Read in full on PubMed Central. doi:10.3389/fnut.2023.1079609
[33] Kerkeni M, Kerkeni M, Ammar A, Aziz AR, Jallouli A, AlSaleh A, et al. 4-week intervention combining kiwifruit consumption and small-sided soccer games improves sleep quality in children with overweight/obesity and pre-existing sleep problems. Nutrition and Health 2025;31(4):1683–1693. 36 children. Read in its published abstract. doi:10.1177/02601060241311385
[34] Duttaroy AK, Jørgensen A. Effects of kiwi fruit consumption on platelet aggregation and plasma lipids in healthy human volunteers. Platelets 2004;15(5):287–292. Read in its published abstract. doi:10.1080/09537100410001710290
[35] Karlsen A, Svendsen M, Seljeflot I, Laake P, Duttaroy AK, Drevon CA, et al. Kiwifruit decreases blood pressure and whole-blood platelet aggregation in male smokers. Journal of Human Hypertension 2013;27(2):126–130. 102 men. Read in its published abstract. doi:10.1038/jhh.2011.116
[36] US Department of Agriculture, FoodData Central: Apples, raw, with skin (SR Legacy, FDC ID 171688). Per 100 g: vitamin C 4.6 mg, dietary fiber 2.4 g, potassium 107 mg, 52 kcal. Read 10 October 2026.
[37] ClinicalTrials.gov NCT03569527. Kiwifruit, prunes, & fiber for abdominal and bowel symptoms in US patients with chronic constipation. The registry record of the trial in [10], with its eligibility rules. Read 10 October 2026.
[38] ClinicalTrials.gov NCT06836024. Actazin (kiwifruit extract) versus polyethylene glycol 3350 for maintenance therapy in children with constipation: a feasibility randomized control trial. Listed as not yet recruiting, record last updated 19 March 2025. Read 10 October 2026.
[39] Bayer SB, Barnett M, Ng HM, Maggo J, Gearry RB. Kiwifruit ingestion to normalise gastrointestinal symptoms (KINGS): a multicentre clinical trial with mechanistic outcomes. ESPEN Congress 2026, ePoster PP397, shown 7 September 2026. A meeting abstract, read in full on the congress’s abstract site on 10 October 2026. It reports belly pain and colon scans, not bowel movements, and counts 52 people in its whole-group analysis and 17 with IBS-C, where the 2024 report in [40] gives 57 and 18. One author declares an honorarium from the kiwifruit marketer to present data at its headquarters. It gives 60 as the number randomised; the published protocol gives both 60 and 63 [27], and the news report 63 [40].
[40] A medical news service’s report of the poster in [42], “Green kiwi may improve GI symptoms in IBS-C patients”, published 10 June 2024 and read in full on 10 October 2026. It gives the trial’s design and p-values for its outcomes, not the size or direction of the differences in bowel movements.
[41] Bangash AM, Naeem H, Anwar MT, Khaqan MA, Farooq S, Rashid M, et al. S823 Kiwifruit and kiwifruit extracts for treatment of constipation in healthy plus functional constipation including irritable bowel syndrome type constipation patient: a meta-analysis. American Journal of Gastroenterology 2024;119(10S):S563–S564. A meeting abstract, read in full in OpenAlex’s copy. It pools eight trials of the fruit and its extracts without naming them; no funding statement was read. doi:10.14309/01.ajg.0001032660.57699.b2
[42] Maggo JK, Ng HM, Bayer SB, Wall CL, Hoad CL, Marciani L, et al. Mo1938 Impact of green kiwifruit on gastrointestinal physiology and constipation symptoms in adults: a randomized controlled trial. Gastroenterology 2024;166(5):S-1180. A poster abstract from a gastroenterology meeting in May 2024. Its text was not read: the journal’s and the publisher’s pages served bot checks, the publisher’s text service refused the request, and Crossref, OpenAlex, Semantic Scholar and the Internet Archive hold no copy. What the trial found is taken from [40] and [39]. doi:10.1016/S0016-5085(24)03173-1
[43] Briskey D, Mallard AR, Rao A. Efficacy of a kiwifruit extract (PhenActiv™) on gastrointestinal tract function: a randomised double-blind placebo-controlled study. Food and Nutrition Sciences 2023;14(12):1281–1295. 64 healthy adults with mild gut discomfort enrolled, 41 analysed. Read in full in the publisher’s copy. A New Zealand company paid for the trial and supplied the product; the authors declare no conflicts. doi:10.4236/fns.2023.1412081
[44] Lewis ED, Crowley DC, Trivedi R, Wolever T, Buggia MA, Graham E, et al. Green and gold kiwifruit powders consumed for 28 days by healthy individuals with occasional constipation are safe and well-tolerated: a randomized controlled trial. Bioactive Carbohydrates and Dietary Fibre 2023;30:100382. Read as its title, its graphical abstract and its chart of who took part (288 randomised to seven groups), from the publisher’s image server; its text was not read, because the publisher refused automated reading and we found no other copy. Its authors include staff of the research firm that ran the trial, of the registered sponsor in [25] and of the company that supplied the powders in [47]. doi:10.1016/j.bcdf.2023.100382
[45] Graham E, McKeen S, Lewis ED, Evans M, Li Z, Henning SM, et al. Actazin® green kiwifruit powder consumption at 600 mg per day for 28 days improves stool form and relieves occasional constipation in healthy individuals: a randomized controlled trial. Bioactive Carbohydrates and Dietary Fibre 2024;32:100436. Read as its title and its figures, from the publisher’s image server; its text, which explains the symbols on its chart of stool form, was not read. Authors from the same organisations as [44], and two from a university nutrition centre. doi:10.1016/j.bcdf.2024.100436
[46] McKeen S, Henning SM, Lewis E, Evans M, Graham E, Jopson N, et al. Livaux® gold kiwifruit powder consumption at 600 mg per day for 28 days increases Faecalibacterium prausnitzii numbers and decreases bloating and hydrogenotrophic species numbers in healthy individuals, consistent with slow fermentation: a randomized controlled trial. Bioactive Carbohydrates and Dietary Fibre 2025;33:100468. 85 people at four North American sites. Read as its abstract, held by OpenAlex, and its figures; its text was not read. Its abstract names the registration in [25]. doi:10.1016/j.bcdf.2025.100468
[47] Blatchford P, Stoklosinski H, Eady S, Wallace A, Butts C, Gearry R, et al. Consumption of kiwifruit capsules increases Faecalibacterium prausnitzii abundance in functionally constipated individuals: a randomised controlled human trial. Journal of Nutritional Science 2017;6:e52. Cited here only for who supplies the two powders: a New Zealand company, which also helped fund that trial. Read in full on PubMed Central. doi:10.1017/jns.2017.52
[48] Nødtvedt ØO, Hansen AL, Bjorvatn B, Pallesen S. The effects of kiwi fruit consumption in students with chronic insomnia symptoms: a randomized controlled trial. Sleep and Biological Rhythms 2017;15(2):159–166. 74 students. Read in its published abstract, with its funding (a Norwegian university and a regional research council) and its conflict statement (none) on the publisher’s page. doi:10.1007/s41105-017-0095-9
[49] Khartode SS. A comparative study in thrombocytopenia induced by dengue fever or viral fever between kiwi and guava: a randomized clinical trial. International Journal of Food and Nutritional Sciences 2022;11(Special Issue 2):1836–1861. 100 hospital patients in Pune, India. Read in full in the journal’s own copy. Registered with the Clinical Trials Registry of India as CTRI/2022/07/043922 on 12 July 2022, before enrolment, as an open-label trial with a target of 40 patients and no sponsor; record read through the World Health Organization’s trial-search portal. The author declares no conflicts.